Reactome | PP2A (Aalpha:B55alpha:Calpha) [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-927845] mRNA Cleaved by SMG6 [cytosol] - Danio rerio [Complex:R-DRE-927854] Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] - Danio rerio
consumedByEvent	[BlackBoxEvent:R-DRE-927813] p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A - Danio rerio [Reaction:R-DRE-9667965] ANKLE2 binds PP2A - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10590246
displayName	PP2A (Aalpha:B55alpha:Calpha) [cytosol]
hasComponent	[DefinedSet:R-DRE-165982-3] Homologues of PPP2R1A [cytosol] [EntityWithAccessionedSequence:R-DRE-165971] ppp2caa [cytosol] [EntityWithAccessionedSequence:R-DRE-377253] ppp2r2ab [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-377182] PP2A (Aalpha:B55alpha:Calpha) [cytosol] - Homo sapiens
maxDepth	3
name	PP2A (Aalpha:B55alpha:Calpha)
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-377182
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-DRE-927813] p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A [Reaction:R-DRE-9667965] ANKLE2 binds PP2A
(hasComponent)	[Complex:R-DRE-927845] mRNA Cleaved by SMG6 [cytosol] [Complex:R-DRE-927854] Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] [Complex:R-DRE-9667967] ANKLE2:PP2A [endoplasmic reticulum membrane]
(activeUnit)	[CatalystActivity:10605132] protein serine/threonine phosphatase activity of ANKLE2:PP2A [endoplasmic reticulum membrane]
(inferredTo)	[Complex:R-HSA-377182] PP2A (Aalpha:B55alpha:Calpha) [cytosol]