Reactome | Caspase cleavage of DCC

Schema > Reaction > Entries

Caspase cleavage of DCC Show undefined attributes

catalystActivity	[CatalystActivity:10579296] aspartic-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10579298
displayName	Caspase cleavage of DCC
eventOf	[Pathway:R-DRE-418889] Caspase activation via Dependence Receptors in the absence of ligand - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-373705] Caspase cleavage of DCC - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-197560] dcc [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase cleavage of DCC
output	[EntityWithAccessionedSequence:R-DRE-373629] dcc [cytosol] [EntityWithAccessionedSequence:R-DRE-373627] dcc [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-373705
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-418889] Caspase activation via Dependence Receptors in the absence of ligand
(inferredTo)	[Reaction:R-HSA-373705] Caspase cleavage of DCC