Reactome | SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine

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SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine Show undefined attributes

catalystActivity	[CatalystActivity:10578790] amino acid transmembrane transporter activity of SLC38A5 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10578792
displayName	SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
eventOf	[Pathway:R-DRE-352230] Amino acid transport across the plasma membrane - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-352182] SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-352178] ligands of SLC38A5 [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
output	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [DefinedSet:R-ALL-352175] ligands of SLC38A5 [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
precedingEvent	[Reaction:R-DRE-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-352182
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-352230] Amino acid transport across the plasma membrane
(inferredTo)	[Reaction:R-HSA-352182] SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine

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