Reactome | LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649768
displayName	LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
eventOf	[Pathway:R-DRE-1834949] Cytosolic sensors of pathogen-associated DNA - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-DRE-3134914] Beta-catenin migrates to the nucleus - Danio rerio
inferredFrom	[Pathway:R-HSA-3134973] LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-3134973
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-1834949] Cytosolic sensors of pathogen-associated DNA
(inferredTo)	[Pathway:R-HSA-3134973] LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production

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