Reactome | CLCN4/5/6 exchange Cl- for H+

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CLCN4/5/6 exchange Cl- for H+ Show undefined attributes

catalystActivity	[CatalystActivity:10604752] antiporter activity of CLCN4/5/6 [endosome membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:171907] endosome lumen [Compartment:74700] endosome membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10604754
displayName	CLCN4/5/6 exchange Cl- for H+
eventOf	[Pathway:R-DRE-2672351] Stimuli-sensing channels - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2730692] CLCN4/5/6 exchange Cl- for H+ - Homo sapiens
input	[SimpleEntity:R-ALL-2731008] Cl- [endosome lumen] [SimpleEntity:R-ALL-70106] H+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CLCN4/5/6 exchange Cl- for H+
output	[SimpleEntity:R-ALL-352022] Cl- [cytosol] [SimpleEntity:R-ALL-74722] H+ [endosome lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-2730692
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-2672351] Stimuli-sensing channels
(inferredTo)	[Reaction:R-HSA-2730692] CLCN4/5/6 exchange Cl- for H+

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