Reactome | Formation of soluble VTN:C5b-C9

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10604472
displayName	Formation of soluble VTN:C5b-C9
eventOf	[Pathway:R-DRE-977606] Regulation of Complement cascade - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2530429] Formation of soluble VTN:C5b-C9 - Homo sapiens
input	[Complex:R-DRE-173713] C8 [extracellular region] [EntityWithAccessionedSequence:R-DRE-173717] c9 [extracellular region] [Complex:R-DRE-2530437] VTN:C5b:C6:C7 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of soluble VTN:C5b-C9
output	[Complex:R-DRE-2530442] VTN:C5b:C6:C7:C8:C9 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-2530429
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-977606] Regulation of Complement cascade
(inferredTo)	[Reaction:R-HSA-2530429] Formation of soluble VTN:C5b-C9

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