Reactome | phospho-yap1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-2028630] p-YAP1:YWHAB [cytosol] - Danio rerio
consumedByEvent	[Reaction:R-DRE-9865226] PP2A dephosphorylates serine-127 of YAP1 - Danio rerio [Reaction:R-DRE-2028644] YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10600432
displayName	phospho-yap1 [cytosol]
endCoordinate	504
hasModifiedResidue	[ModifiedResidue:10600430] O-phospho-L-serine at 127 (in Homo sapiens)
inDisease	false
inferredFrom	[DefinedSet:R-HSA-2028622] p-YAP1 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2028553] p-S127-YAP1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-yap1 p-S127-YAP1 Q1L8J7
producedByEvent	[Reaction:R-DRE-2028583] Phosphorylation of YAP by LATS2 - Danio rerio
referenceEntity	[ReferenceGeneProduct:uniprot:Q1L8J7] UniProt:Q1L8J7
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-2028553
startCoordinate	1

(input)	[Reaction:R-DRE-9865226] PP2A dephosphorylates serine-127 of YAP1 [Reaction:R-DRE-2028644] YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1
(hasComponent)	[Complex:R-DRE-2028630] p-YAP1:YWHAB [cytosol]
(inferredTo)	[DefinedSet:R-HSA-2028622] p-YAP1 [cytosol] [EntityWithAccessionedSequence:R-HSA-2028553] p-S127-YAP1 [cytosol]
(output)	[Reaction:R-DRE-2028583] Phosphorylation of YAP by LATS2

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