Reactome | Removal of fibrillar collagen C-propeptides

Schema > Reaction > Entries

Removal of fibrillar collagen C-propeptides Show undefined attributes

catalystActivity	[CatalystActivity:10599242] metalloendopeptidase activity of Procollagen C-proteinases [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10599254
displayName	Removal of fibrillar collagen C-propeptides
eventOf	[Pathway:R-DRE-1650814] Collagen biosynthesis and modifying enzymes - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Polymerisation:R-DRE-1474266] Formation of collagen fibrils - Danio rerio
inferredFrom	[Reaction:R-HSA-2002440] Removal of fibrillar collagen C-propeptides - Homo sapiens
input	[DefinedSet:R-DRE-2268931] Fibrillar procollagens -N [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Removal of fibrillar collagen C-propeptides
output	[DefinedSet:R-DRE-2060921] Tropocollagens [extracellular region]
precedingEvent	[Reaction:R-DRE-2002428] Removal of fibrillar collagen N-propeptides - Danio rerio
regulatedBy	[PositiveRegulation:10599255] Positive regulation by 'PCOLCEs [extracellular region]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-2002440
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-1650814] Collagen biosynthesis and modifying enzymes
(precedingEvent)	[Polymerisation:R-DRE-1474266] Formation of collagen fibrils
(inferredTo)	[Reaction:R-HSA-2002440] Removal of fibrillar collagen C-propeptides

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