Reactome | AKT phosphorylates targets in the nucleus

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AKT phosphorylates targets in the nucleus Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648662
displayName	AKT phosphorylates targets in the nucleus
eventOf	[Pathway:R-DRE-1257604] PIP3 activates AKT signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:172430] phosphatidylinositol 3-kinase/protein kinase B signal transduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-199298] AKT phosphorylates CREB1 - Danio rerio [Reaction:R-DRE-199299] AKT phosphorylates FOXO transcription factors - Danio rerio [Reaction:R-DRE-199863] AKT can phosphorylate NR4A1 (NUR77) - Danio rerio
inferredFrom	[Pathway:R-HSA-198693] AKT phosphorylates targets in the nucleus - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	AKT phosphorylates targets in the nucleus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-198693
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-1257604] PIP3 activates AKT signaling
(inferredTo)	[Pathway:R-HSA-198693] AKT phosphorylates targets in the nucleus

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