Reactome | PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-1369085] PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-1370500] PRLR binds SCF beta-TrCP complex - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10590944
displayName	PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane]
hasComponent	[Complex:R-DRE-1675474] p(S349)-PRLR:JAK2 dimer [plasma membrane] [DefinedSet:R-DRE-1172021] Prolactin receptor ligands [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-1977946] PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] - Homo sapiens
maxDepth	5
name	PRLR ligands:p-S349-PRLR:JAK2 dimer
producedByEvent	[BlackBoxEvent:R-DRE-1370505] PRLR is phosphorylated at Ser-349 - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-1977946
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-1370500] PRLR binds SCF beta-TrCP complex
(output)	[BlackBoxEvent:R-DRE-1370505] PRLR is phosphorylated at Ser-349
(hasComponent)	[Complex:R-DRE-1369085] PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(inferredTo)	[Complex:R-HSA-1977946] PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane]

Cite Us!