Reactome | Down Regulation of Emi1 through Phosphorylation of Emi1

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Down Regulation of Emi1 through Phosphorylation of Emi1 Show undefined attributes

catalystActivity	[CatalystActivity:10568781] protein serine/threonine kinase activity of p-T210-PLK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10569428
displayName	Down Regulation of Emi1 through Phosphorylation of Emi1
eventOf	[Pathway:R-DRE-68881] Mitotic Metaphase/Anaphase Transition - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-163010] Down Regulation of Emi1 through Phosphorylation of Emi1 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-174060] FBXO5 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Down Regulation of Emi1 through Phosphorylation of Emi1
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-163049] phospho-p-FBXO5 [nucleoplasm]
precedingEvent	[Reaction:R-DRE-3002798] Cytosolic PLK1 translocates to the nucleus - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-163010
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-68881] Mitotic Metaphase/Anaphase Transition
(inferredTo)	[Reaction:R-HSA-163010] Down Regulation of Emi1 through Phosphorylation of Emi1

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