Reactome | Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10593092] non-membrane spanning protein tyrosine kinase activity of Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-DRE-1112602] Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10593083
displayName	Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-DRE-629622] stat1a [cytosol] [Complex:R-DRE-1112594] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1112576] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] - Homo sapiens
maxDepth	7
name	Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3
producedByEvent	[Reaction:R-DRE-1112565] Tyrosine phosphorylated IL6ST binds STAT1,STAT3 - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-1112576
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-1112602] Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor
(physicalEntity)	[CatalystActivity:10593092] non-membrane spanning protein tyrosine kinase activity of Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane]
(output)	[Reaction:R-DRE-1112565] Tyrosine phosphorylated IL6ST binds STAT1,STAT3
(inferredTo)	[Complex:R-HSA-1112576] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane]

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