Reactome | CCNA:CDK1 phosphorylates WEE1

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CCNA:CDK1 phosphorylates WEE1 Show undefined attributes

catalystActivity	[CatalystActivity:10909334] cyclin-dependent protein serine/threonine kinase activity of p-S-CCNA:p-T161-CDK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10909336
displayName	CCNA:CDK1 phosphorylates WEE1
eventOf	[Pathway:R-DME-69273] Cyclin A/B1/B2 associated events during G2/M transition - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9929535] CCNA:CDK1 phosphorylates WEE1 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-69253] WEE1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CCNA:CDK1 phosphorylates WEE1
output	2 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-9929669] phospho-p-T187,T190-WEE1 [nucleoplasm]
precedingEvent	[Reaction:R-DME-9929514] CDK1 phosphorylates CCNA - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9929535
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-69273] Cyclin A/B1/B2 associated events during G2/M transition
(inferredTo)	[Reaction:R-HSA-9929535] CCNA:CDK1 phosphorylates WEE1