Reactome | CASP8 cleaves N4BP1 at D424, D490

Schema > BlackBoxEvent > Entries

CASP8 cleaves N4BP1 at D424, D490 Show undefined attributes

catalystActivity	[CatalystActivity:10905149] cysteine-type peptidase activity of active caspase-8 [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10905151
displayName	CASP8 cleaves N4BP1 at D424, D490
eventOf	[Pathway:R-DME-9758274] Regulation of NF-kappa B signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160781] regulation of canonical NF-kappaB signal transduction
inferredFrom	[BlackBoxEvent:R-HSA-9757951] CASP8 cleaves N4BP1 at D424, D490 - Homo sapiens
input	2 × [DefinedSet:R-DME-9757941-3] Homologues of N4BP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CASP8 cleaves N4BP1 at D424, D490
output	[DefinedSet:R-DME-9757962] N4BP1(1-424), N4BP1(1-490) [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9757951
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9758274] Regulation of NF-kappa B signaling
(inferredTo)	[BlackBoxEvent:R-HSA-9757951] CASP8 cleaves N4BP1 at D424, D490

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