Reactome | phospho-foxo [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-9614628] p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-9614562] 14-3-3 proteins bind AKT-phosphorylated FOXO3 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10902973
displayName	phospho-foxo [cytosol]
endCoordinate	673
hasModifiedResidue	[ModifiedResidue:10843213] O-phospho-L-serine at 253 (in Homo sapiens) [ModifiedResidue:10843214] O-phospho-L-serine at 315 (in Homo sapiens) [ModifiedResidue:10843215] O-phospho-L-threonine at 32 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9614413] p-T32,S253,S315-FOXO3 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-foxo p-T32,S253,S315-FOXO3 Q95V55
producedByEvent	[BlackBoxEvent:R-DME-9699581] AKT-phosphorylated FOXO3 translocates to cytosol - Drosophila melanogaster [BlackBoxEvent:R-DME-9624527] AKT-phosphorylated FOXO3 translocates to cytosol - Drosophila melanogaster
referenceEntity	[ReferenceGeneProduct:uniprot:Q95V55] UniProt:Q95V55 foxo
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9614413
startCoordinate	2

(output)	[BlackBoxEvent:R-DME-9699581] AKT-phosphorylated FOXO3 translocates to cytosol [BlackBoxEvent:R-DME-9624527] AKT-phosphorylated FOXO3 translocates to cytosol
(input)	[Reaction:R-DME-9614562] 14-3-3 proteins bind AKT-phosphorylated FOXO3
(hasComponent)	[Complex:R-DME-9614628] p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9614413] p-T32,S253,S315-FOXO3 [cytosol]

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