Reactome | K48polyUb [cytosol]

Schema > Polymer > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-9948363] peptidyl-tRNA with K48polyUb-nascent peptide-Alanine [cytosol] - Drosophila melanogaster [Complex:R-DME-9948421] K48polyUb-nascent peptide-Alanine [cytosol] - Drosophila melanogaster
consumedByEvent	[BlackBoxEvent:R-DME-5675470] BIRC2/3 (cIAP1/2) is autoubiquitinated - Drosophila melanogaster [Reaction:R-DME-5690827] TNFAIP3 (A20) ubiquitinates RIPK1 - Drosophila melanogaster [BlackBoxEvent:R-DME-912627] CBL ubiquitinates PI3K - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10857679
displayName	K48polyUb [cytosol]
inDisease	false
inferredFrom	[Polymer:R-HSA-912740] K48polyUb [cytosol] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-DME-5689096] PolyUb [cytosol] - Drosophila melanogaster
name	K48polyUb
producedByEvent	[Reaction:R-DME-5690870] OTUD7B,TNFAIP3 deubiquitinate TRAF6 - Drosophila melanogaster [Reaction:R-DME-5690196] USP8 deubiquitinates RNF128 - Drosophila melanogaster
repeatedUnit	[DefinedSet:R-DME-912722] K48-Ub [cytosol]
schemaClass	Polymer
species	[Species:56210] Drosophila melanogaster
stId	R-DME-912740
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-DME-9948363] peptidyl-tRNA with K48polyUb-nascent peptide-Alanine [cytosol] [Complex:R-DME-9948421] K48polyUb-nascent peptide-Alanine [cytosol]
(input)	[Reaction:R-DME-5690827] TNFAIP3 (A20) ubiquitinates RIPK1 [BlackBoxEvent:R-DME-912627] CBL ubiquitinates PI3K [BlackBoxEvent:R-DME-5675470] BIRC2/3 (cIAP1/2) is autoubiquitinated
(output)	[Reaction:R-DME-5690870] OTUD7B,TNFAIP3 deubiquitinate TRAF6 [Reaction:R-DME-5690196] USP8 deubiquitinates RNF128
(hasMember)	[DefinedSet:R-DME-5689096] PolyUb [cytosol]
(inferredTo)	[Polymer:R-HSA-912740] K48polyUb [cytosol]