Reactome | CDC42 GTPase cycle

Schema > Pathway > Entries

CDC42 GTPase cycle Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10913186
displayName	CDC42 GTPase cycle
eventOf	[Pathway:R-DME-9012999] RHO GTPase cycle - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-9013159] CDC42 GEFs activate CDC42 - Drosophila melanogaster [Reaction:R-DME-9013161] CDC42 GAPs stimulate CDC42 GTPase activity - Drosophila melanogaster [Reaction:R-DME-9013158] CDC42 GDIs block activation of CDC42 - Drosophila melanogaster [BlackBoxEvent:R-DME-9692800] CDC42 translocates to the endoplasmic reticulum membrane - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-9013148] CDC42 GTPase cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CDC42 GTPase cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9013148
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-9012999] RHO GTPase cycle
(inferredTo)	[Pathway:R-HSA-9013148] CDC42 GTPase cycle

© 2026 Reactome

Cite Us!