Reactome | ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10860922
displayName	ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol]
hasComponent	[Complex:R-DME-8932458] PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] [Complex:R-DME-1234113] ub-hydroxyPro-HIF-alpha [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8932472] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] - Homo sapiens
maxDepth	5
memberOf	[DefinedSet:R-DME-8932465] ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] - Drosophila melanogaster
name	ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3
producedByEvent	[Reaction:R-DME-1234163] Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8932472
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-DME-8932465] ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol]
(output)	[Reaction:R-DME-1234163] Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha
(inferredTo)	[Complex:R-HSA-8932472] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol]

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