Reactome | PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10861011] peptidyl-proline 4-dioxygenase activity of PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-8932472] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] - Drosophila melanogaster [Complex:R-DME-1234125] hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-1234183] Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10860920
displayName	PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-DME-8932473] jub [cytosol] [DefinedSet:R-DME-1234122] PHD2,3 [cytosol] [Complex:R-DME-976093] RBX1-CUL2-EloB,C-VHL [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8932458] PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-DME-8932481] VBC complex (with or without LIMD1) [cytosol] - Drosophila melanogaster
name	PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-8932458
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-DME-8932481] VBC complex (with or without LIMD1) [cytosol]
(hasComponent)	[Complex:R-DME-8932472] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] [Complex:R-DME-1234125] hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol]
(input)	[Reaction:R-DME-1234183] Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha
(physicalEntity)	[CatalystActivity:10861011] peptidyl-proline 4-dioxygenase activity of PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]
(inferredTo)	[Complex:R-HSA-8932458] PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]