Reactome | conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate

Schema > Reaction > Entries

conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate Show undefined attributes

catalystActivity	[CatalystActivity:10832963] beta-ureidopropionase activity of UPB1:Zn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10833011
displayName	conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate
eventOf	[Pathway:R-DME-73621] Pyrimidine catabolism - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-73620] conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate - Homo sapiens
input	2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-73617] UIBA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate 3-(carbamoylamino)-2-methylpropanoate + H2O + 2 H(+) => (R)-3-amino-2-methylpropanoate + NH4(+) + CO2
output	[SimpleEntity:R-ALL-73619] 3AIB [cytosol] [SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
precedingEvent	[Reaction:R-DME-73618] conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-73620
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-73621] Pyrimidine catabolism
(inferredTo)	[Reaction:R-HSA-73620] conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate

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