Reactome | TP53 family members bind PPP1R13B or TP53BP2

Schema > Reaction > Entries

TP53 family members bind PPP1R13B or TP53BP2 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10890517
displayName	TP53 family members bind PPP1R13B or TP53BP2
eventOf	[Pathway:R-DME-6804759] Regulation of TP53 Activity through Association with Co-factors - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6799777] TP53 family members bind PPP1R13B or TP53BP2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-6799775] ASPP [nucleoplasm] [DefinedSet:R-DME-6798076] p-S15,S20-TP53,TP63,TP73 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TP53 family members bind PPP1R13B or TP53BP2 p53 family members bind ASPP1 or ASPP2
output	[Complex:R-DME-6799788] (p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2) [nucleoplasm]
precedingEvent	[Reaction:R-DME-6799246] CHEK1 phosphorylates TP53 - Drosophila melanogaster [Reaction:R-DME-69685] CHEK2 phosphorylates TP53 - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6799777
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-6804759] Regulation of TP53 Activity through Association with Co-factors
(inferredTo)	[Reaction:R-HSA-6799777] TP53 family members bind PPP1R13B or TP53BP2

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