Reactome | CHST4 transfers SO4(2-) from PAPS to Core 2 mucins

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CHST4 transfers SO4(2-) from PAPS to Core 2 mucins Show undefined attributes

catalystActivity	[CatalystActivity:10885740] N-acetylglucosamine 6-O-sulfotransferase activity of CHST4 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10885742
displayName	CHST4 transfers SO4(2-) from PAPS to Core 2 mucins
eventOf	[Pathway:R-DME-913709] O-linked glycosylation of mucins - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6786012] CHST4 transfers SO4(2-) from PAPS to Core 2 mucins - Homo sapiens
input	[DefinedSet:R-DME-1462066] Core 2 mucins [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CHST4 transfers SO4(2-) from PAPS to Core 2 mucins
output	[DefinedSet:R-DME-6786346] Core 2S mucins [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-DME-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6786012
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-913709] O-linked glycosylation of mucins
(inferredTo)	[Reaction:R-HSA-6786012] CHST4 transfers SO4(2-) from PAPS to Core 2 mucins

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