Reactome | Fanconi Anemia Pathway

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912940
displayName	Fanconi Anemia Pathway
eventOf	[TopLevelPathway:R-DME-73894] DNA Repair - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2454420] interstrand cross-link repair
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-6785594] FANCD2 binds FANCI - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-6783310] Fanconi Anemia Pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Fanconi Anemia Pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6783310
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DME-73894] DNA Repair
(hasEncapsulatedEvent)	[Pathway:R-DME-6796648] TP53 Regulates Transcription of DNA Repair Genes
(inferredTo)	[Pathway:R-HSA-6783310] Fanconi Anemia Pathway

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