Reactome | Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER

Schema > Reaction > Entries

Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER Show undefined attributes

catalystActivity	[CatalystActivity:10885253] DNA-directed DNA polymerase activity of TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10885255
displayName	Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
eventOf	[Pathway:R-DME-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-6782227] Ligation of newly synthesized repair patch to incised DNA in TC-NER - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Homo sapiens
input	[SimpleEntity:R-ALL-30555] dNTP [nucleoplasm] [Complex:R-DME-6782222] TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
output	[SimpleEntity:R-ALL-113541] PPi [nucleoplasm] [Complex:R-DME-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6782208
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER
(precedingEvent)	[Reaction:R-DME-6782227] Ligation of newly synthesized repair patch to incised DNA in TC-NER
(inferredTo)	[Reaction:R-HSA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER

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