Reactome | USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1

Schema > Reaction > Entries

USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 Show undefined attributes

catalystActivity	[CatalystActivity:10715176] cysteine-type deubiquitinase activity of USP17:PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
dbId	10715178
displayName	USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1
eventOf	[Pathway:R-DME-5689880] Ub-specific processing proteases - Drosophila melanogaster
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5696600] USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-DME-6782800] USP17:PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1 [cytosol]
isInDisease	false
isInferred	true
name	USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1
output	[DefinedSet:R-DME-5689096] PolyUb [cytosol] [Complex:R-DME-6782822] USP17L1,USP17L2:RCE1, CDC25A, DDX58, IFIH1 [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5696600
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-5689880] Ub-specific processing proteases
(inferredTo)	[Reaction:R-HSA-5696600] USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1

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