Reactome | CRYM reduces P2C to PPCA

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CRYM reduces P2C to PPCA Show undefined attributes

catalystActivity	[CatalystActivity:10883740] delta1-piperideine-2-carboxylate reductase activity of CRYM [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10883742
displayName	CRYM reduces P2C to PPCA
eventOf	[Pathway:R-DME-71064] Lysine catabolism - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5693347] CRYM reduces P2C to PPCA - Homo sapiens
input	[SimpleEntity:R-ALL-193465] H+ [peroxisomal matrix] [SimpleEntity:R-ALL-113602] NADPH [peroxisomal matrix] [SimpleEntity:R-ALL-5693311] P2C [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	CRYM reduces P2C to PPCA Delta(1)-piperideine-2-carboxylate + H(+) + NADPH => L-pipecolate + NADP(+)
output	[SimpleEntity:R-ALL-389556] NADP+ [peroxisomal matrix] [SimpleEntity:R-ALL-5693325] PPCA [peroxisomal matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5693347
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-71064] Lysine catabolism
(inferredTo)	[Reaction:R-HSA-5693347] CRYM reduces P2C to PPCA

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