Reactome | KAL1 binds FGFR1c

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10880265
displayName	KAL1 binds FGFR1c
eventOf	[Pathway:R-DME-5654726] Negative regulation of FGFR1 signaling - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5654514] KAL1 binds FGFR1c - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-189897] FGFR1c [plasma membrane] [EntityWithAccessionedSequence:R-DME-5654345] Kal1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	KAL1 binds FGFR1c
output	[Complex:R-DME-5654346] FGFR1c:KAL1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5654514
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-5654726] Negative regulation of FGFR1 signaling
(inferredTo)	[Reaction:R-HSA-5654514] KAL1 binds FGFR1c