Reactome | Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10880230] guanyl-nucleotide exchange factor activity of Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10880223
displayName	Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane]
hasComponent	[Complex:R-DME-5654340] Activated FGFR4:pY-SHC1 [plasma membrane] [Complex:R-DME-109797] GRB2-1:SOS1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654343] Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] - Homo sapiens
maxDepth	6
memberOf	[DefinedSet:R-DME-5672601] RAS GEFs [plasma membrane] - Drosophila melanogaster
name	Activated FGFR4:pY-SHC1:GRB2:SOS1
producedByEvent	[Reaction:R-DME-5654423] Activated FGFR4:p-SHC1 binds GRB2:SOS1 - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5654343
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10880230] guanyl-nucleotide exchange factor activity of Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane]
(output)	[Reaction:R-DME-5654423] Activated FGFR4:p-SHC1 binds GRB2:SOS1
(hasMember)	[DefinedSet:R-DME-5672601] RAS GEFs [plasma membrane]
(inferredTo)	[Complex:R-HSA-5654343] Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane]

Cite Us!