Reactome | SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+

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SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ Show undefined attributes

catalystActivity	[CatalystActivity:10879611] calcium, potassium:sodium antiporter activity of SLC24A5 [trans-Golgi network membrane]
category	transition
compartment	[Compartment:263163] trans-Golgi network membrane [Compartment:70101] cytosol [Compartment:17963] Golgi lumen
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10879613
displayName	SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+
eventOf	[Pathway:R-DME-425561] Sodium/Calcium exchangers - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5626316] SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ - Homo sapiens
input	[SimpleEntity:R-ALL-167012] Ca2+ [Golgi lumen] [SimpleEntity:R-ALL-5626313] K+ [Golgi lumen] 4 × [SimpleEntity:R-ALL-83910] Na+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol] [SimpleEntity:R-ALL-29804] K+ [cytosol] 4 × [SimpleEntity:R-ALL-425958] Na+ [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5626316
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-425561] Sodium/Calcium exchangers
(inferredTo)	[Reaction:R-HSA-5626316] SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+

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