Reactome | Hikeshi binds HSP70s:ATP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10876830
displayName	Hikeshi binds HSP70s:ATP
eventOf	[Pathway:R-DME-3371453] Regulation of HSF1-mediated heat shock response - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5251942] Hikeshi binds HSP70s:ATP - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-5216031] Hikeshi [cytosol] [CandidateSet:R-DME-5252049] HSP70s:ATP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Hikeshi binds HSP70s:ATP Hikeshi (C11orf73) binds ATP-bound heat-shock 70 proteins in the cytosol - leave here
output	[Complex:R-DME-5252091] Hikeshi:HSP70s:ATP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-5251942
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-3371453] Regulation of HSF1-mediated heat shock response
(inferredTo)	[Reaction:R-HSA-5251942] Hikeshi binds HSP70s:ATP

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