Reactome | Transcription repression by PER and activation by PDP1

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Transcription repression by PER and activation by PDP1 Show undefined attributes

authored	[InstanceEdit:432420] Williams, MG, 2009-08-13
created	[InstanceEdit:432644] Williams, MG, 2009-08-14
crossReference	[DatabaseIdentifier:12819453] BioModels Database:BIOMD0000000160 [DatabaseIdentifier:12819691] BioModels Database:BIOMD0000000022
dbId	432501
displayName	Transcription repression by PER and activation by PDP1
edited	[InstanceEdit:432644] Williams, MG, 2009-08-14
eventOf	[Pathway:R-DME-432626] Circadian Clock pathway - Drosophila melanogaster
followingEvent	[Pathway:R-DME-432620] Dephosphorylation of PER - Drosophila melanogaster [Pathway:R-DME-432395] Degradation of TIM - Drosophila melanogaster
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-538900] Phosphorylated PER rebinds to phosphorylated TIM - Drosophila melanogaster [Reaction:R-DME-538904] Phosphorylated PER binds to CLK - Drosophila melanogaster [Reaction:R-DME-432513] CLK is phosphorylated by DCO - Drosophila melanogaster [Reaction:R-DME-538891] CLK:CYC heterodimer dissociates from per, tim, vri, and Pdp1 genes - Drosophila melanogaster [Reaction:R-DME-432381] PDP1 replaces VRI as binder to Clk and cry genes - Drosophila melanogaster
isInDisease	false
isInferred	false
lastUpdatedDate	2020-03-16
literatureReference	[LiteratureReference:432523] The circadian timekeeping system of Drosophila
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Transcription repression by PER and activation by PDP1
precedingEvent	[Pathway:R-DME-432490] Nuclear import of PER and TIM - Drosophila melanogaster
releaseDate	2010-07-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:909536] Edery, I, 2010-07-06
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-432501
summation	[Summation:9038601] Spatzle (SPZ) dimer binding leads to Toll (TL) receptor homo...
updateTrackers	[UpdateTracker:9779327] Update Tracker - [Pathway:432501] Transcription repression by PER and activation by PDP1 - v65:[addSummation] [UpdateTracker:9777407] Update Tracker - [Pathway:432501] Transcription repression by PER and activation by PDP1 - v72:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9779327] Update Tracker - [Pathway:432501] Transcription repression by PER and activation by PDP1 - v65:[addSummation] [UpdateTracker:9777407] Update Tracker - [Pathway:432501] Transcription repression by PER and activation by PDP1 - v72:[modifyText]
(hasEvent)	[Pathway:R-DME-432626] Circadian Clock pathway
(precedingEvent)	[Pathway:R-DME-432620] Dephosphorylation of PER [Pathway:R-DME-432395] Degradation of TIM

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