Reactome | GP1b-IX-V activation signalling

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912074
displayName	GP1b-IX-V activation signalling
eventOf	[Pathway:R-DME-76002] Platelet activation, signaling and aggregation - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-443831] 14-3-3-zeta binds Raf1 - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-430116] GP1b-IX-V activation signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	GP1b-IX-V activation signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-430116
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-76002] Platelet activation, signaling and aggregation
(inferredTo)	[Pathway:R-HSA-430116] GP1b-IX-V activation signalling

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