Reactome | Phosphorylated HPO dimer phosphorylates WTS

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Phosphorylated HPO dimer phosphorylates WTS Show undefined attributes

authored	[InstanceEdit:390144] Williams, MG, 2009-01-23 09:43:46
catalystActivity	[CatalystActivity:451797] protein serine/threonine kinase activity of MATS:Phospho HPO dimer:Phospho SAV:WTS [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
dbId	390112
displayName	Phosphorylated HPO dimer phosphorylates WTS
edited	[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
eventOf	[Pathway:R-DME-390089] Formation of the Hippo kinase cassette - Drosophila melanogaster
figure	[Figure:451884] /figures/DrosBHippoW09.jpg
followingEvent	[Reaction:R-DME-390154] MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS - Drosophila melanogaster
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DME-451860] MATS:Phospho HPO dimer:Phospho SAV:WTS [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:390080] hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts [LiteratureReference:390188] The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated HPO dimer phosphorylates WTS
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DME-390172] MATS:Phospho HPO dimer:Phospho SAV:Phospho WTS [cytosol]
precedingEvent	[Reaction:R-DME-390145] Phosphorylated HPO dimer phosphorylates SAV - Drosophila melanogaster
releaseDate	2010-07-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:909538] Irvine, KD, 2009-11-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-390112
summation	[Summation:390130] Activated Hippo (HPO) serine/threonine kinase homodimer phos...

Referrals

(hasEvent)	[Pathway:R-DME-390089] Formation of the Hippo kinase cassette
(precedingEvent)	[Reaction:R-DME-390154] MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS

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