Reactome | TCF/LEF:CTNNB1 [nucleoplasm]

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TCF/LEF:CTNNB1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-3322393] TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-3322396] TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-3322424] Beta-catenin recruits CDC73 and LEO1 - Drosophila melanogaster [Reaction:R-DME-3322427] Beta-catenin recruits CBP/p300 - Drosophila melanogaster [Reaction:R-DME-3451153] Beta-catenin recruits TRRAP/KAT5 HAT components - Drosophila melanogaster [Reaction:R-DME-5665608] TCF:Beta-catenin binds SOX proteins - Drosophila melanogaster [Reaction:R-DME-8951428] RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10873379
displayName	TCF/LEF:CTNNB1 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DME-3451168] arm [nucleoplasm] [EntityWithAccessionedSequence:R-DME-201923] pan [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-8951429] CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] - Homo sapiens [Complex:R-HSA-3299548] TCF/LEF:CTNNB1 [nucleoplasm] - Homo sapiens
maxDepth	2
name	TCF/LEF:CTNNB1
producedByEvent	[Reaction:R-DME-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-3299548
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-DME-3322424] Beta-catenin recruits CDC73 and LEO1 [Reaction:R-DME-3322427] Beta-catenin recruits CBP/p300 [Reaction:R-DME-3451153] Beta-catenin recruits TRRAP/KAT5 HAT components [Reaction:R-DME-5665608] TCF:Beta-catenin binds SOX proteins [Reaction:R-DME-8951428] RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7)
(hasComponent)	[Complex:R-DME-3322393] TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] [Complex:R-DME-3322396] TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] [Complex:R-DME-3451129] TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] [Complex:R-DME-5665607] TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] [Complex:R-DME-8951432] RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm]
(output)	[Reaction:R-DME-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF
(inferredTo)	[Complex:R-HSA-3299548] TCF/LEF:CTNNB1 [nucleoplasm] [Complex:R-HSA-8951429] CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm]

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