Reactome | MAPKs phosphorylate ETS1 and ETS2

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MAPKs phosphorylate ETS1 and ETS2 Show undefined attributes

catalystActivity	[CatalystActivity:10843034] protein serine/threonine kinase activity of p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10872634
displayName	MAPKs phosphorylate ETS1 and ETS2
eventOf	[Pathway:R-DME-2559585] Oncogene Induced Senescence - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-3209165] ID1 sequesters ETS2 - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-3132737] MAPKs phosphorylate ETS1 and ETS2 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-1629809] pnt [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPKs phosphorylate ETS1 and ETS2
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-DME-3132720] phospho-pnt [nucleoplasm]
precedingEvent	[Reaction:R-DME-5674385] p-T,Y MAPKs dimerize - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-3132737
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-2559585] Oncogene Induced Senescence
(precedingEvent)	[Reaction:R-DME-3209165] ID1 sequesters ETS2
(inferredTo)	[Reaction:R-HSA-3132737] MAPKs phosphorylate ETS1 and ETS2

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