Reactome | PLK1 phosphorylates GORASP1

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PLK1 phosphorylates GORASP1 Show undefined attributes

catalystActivity	[CatalystActivity:10870797] protein serine/threonine kinase activity of p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10870799
displayName	PLK1 phosphorylates GORASP1
eventOf	[Pathway:R-DME-162658] Golgi Cisternae Pericentriolar Stack Reorganization - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2214351] PLK1 phosphorylates GORASP1 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DME-2172193] p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PLK1 phosphorylates GORASP1 Activation of the Anaphase Promoting Complex (APC) by PLK1
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DME-2314414] p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-2214351
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-162658] Golgi Cisternae Pericentriolar Stack Reorganization
(inferredTo)	[Reaction:R-HSA-2214351] PLK1 phosphorylates GORASP1

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