Reactome | Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex'

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Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex' Show undefined attributes

authored	[InstanceEdit:386950] Williams, MG, 2006-07-26 16:49:12
catalystActivity	[CatalystActivity:208868] ubiquitin-protein transferase activity of SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:206331] Williams, MG, 2006-10-24 13:03:16
dbId	209094
displayName	Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex'
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
eventOf	[Pathway:R-DME-209461] Ubiquitination and degradation of phosphorylated ARM - Drosophila melanogaster
figure	[Figure:208613] /figures/BDrosWing10.jpg
followingEvent	[BlackBoxEvent:R-DME-209129] Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex - Drosophila melanogaster [Reaction:R-DME-209097] ARM binds to APC and AXN in the 'destruction complex' - Drosophila melanogaster [Reaction:R-DME-209102] SLMB binds to phosphorylated ARM to form the 'destruction complex' - Drosophila melanogaster
input	[Complex:R-DME-207002] SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] [DefinedSet:R-DME-206204] UBI-P63E [cytosol]
isInDisease	false
isInferred	false
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex'
output	[Complex:R-DME-206602] Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] [Complex:R-DME-206788] SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] [Complex:R-DME-206991] UBI-P63E:Phospho (4 sites) ARM [cytosol]
precedingEvent	[Reaction:R-DME-209102] SLMB binds to phosphorylated ARM to form the 'destruction complex' - Drosophila melanogaster
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386952] Nusse, Roel, 2008-01-19
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-209094
summation	[Summation:206452] The bound and phosphorylated Armadillo (ARM) is ubiquitated ...

Referrals

(precedingEvent)	[BlackBoxEvent:R-DME-209129] Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex [Reaction:R-DME-209097] ARM binds to APC and AXN in the 'destruction complex' [Reaction:R-DME-209102] SLMB binds to phosphorylated ARM to form the 'destruction complex'
(hasEvent)	[Pathway:R-DME-209461] Ubiquitination and degradation of phosphorylated ARM

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