Reactome | Phospho-R-Smad1/5/8 forms a complex with Co-Smad

Schema > Reaction > Entries

Phospho-R-Smad1/5/8 forms a complex with Co-Smad Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10843578
displayName	Phospho-R-Smad1/5/8 forms a complex with Co-Smad
eventOf	[Pathway:R-DME-201451] Signaling by BMP - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - Homo sapiens
input	[EntityWithAccessionedSequence:R-DME-170862] Med [cytosol] 2 × [DefinedSet:R-DME-201482] p-2S-SMAD1/5/8 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phospho-R-Smad1/5/8 forms a complex with Co-Smad
output	[Complex:R-DME-201419] p-2S-SMAD1/5/8:SMAD4 [cytosol]
precedingEvent	[Reaction:R-DME-201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-201422
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-201451] Signaling by BMP
(precedingEvent)	[Reaction:R-DME-201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus
(inferredTo)	[Reaction:R-HSA-201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad

Cite Us!