Reactome | phospho-p-T308,S473-AKT1 [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DME-202323] p-T308,S473-AKT1:PIP3 [plasma membrane] - Drosophila melanogaster [Complex:R-DME-202113] eNOS:CaM:HSP90:p-AKT1 [plasma membrane] - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10843914
displayName	phospho-p-T308,S473-AKT1 [plasma membrane]
endCoordinate	480
hasModifiedResidue	[ModifiedResidue:164809] O-phospho-L-threonine at 308 [ModifiedResidue:164808] O-phospho-L-serine at 473
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-199430] p-T308,S473-AKT1 [plasma membrane] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-DME-432180] AKT1/PDK1 [plasma membrane] - Drosophila melanogaster
name	phospho-p-T308,S473-AKT1 Q8INB9
referenceEntity	[ReferenceGeneProduct:uniprot:Q8INB9] UniProt:Q8INB9 Akt
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-199430
startCoordinate	1

(hasMember)	[DefinedSet:R-DME-432180] AKT1/PDK1 [plasma membrane]
(activeUnit)	[CatalystActivity:10908330] protein serine kinase activity of p-T308,S473-AKT1:PIP3 [plasma membrane] [CatalystActivity:10843926] protein serine/threonine kinase activity of eNOS:CaM:HSP90:p-AKT1 [plasma membrane]
(hasComponent)	[Complex:R-DME-202323] p-T308,S473-AKT1:PIP3 [plasma membrane] [Complex:R-DME-202113] eNOS:CaM:HSP90:p-AKT1 [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-199430] p-T308,S473-AKT1 [plasma membrane]

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