Reactome | 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP

Schema > Reaction > Entries

3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP Show undefined attributes

catalystActivity	[CatalystActivity:10840589] aryl sulfotransferase activity of SULT dimers (T3) [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10840591
displayName	3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP
eventOf	[Pathway:R-DME-156584] Cytosolic sulfonation of small molecules - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP - Homo sapiens
input	[SimpleEntity:R-ALL-158471] PAPS [cytosol] [SimpleEntity:R-ALL-176667] T3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP
output	[SimpleEntity:R-ALL-176564] 3,5,3'-triiodothyronine 4-sulfate [cytosol] [SimpleEntity:R-ALL-158466] PAP [cytosol]
precedingEvent	[Reaction:R-DME-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-176585
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-156584] Cytosolic sulfonation of small molecules
(precedingEvent)	[Reaction:R-DME-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
(inferredTo)	[Reaction:R-HSA-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP

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