Reactome | Cytosolic sulfonation of small molecules

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Cytosolic sulfonation of small molecules Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911400
displayName	Cytosolic sulfonation of small molecules
eventOf	[Pathway:R-DME-156580] Phase II - Conjugation of compounds - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:80798] 3'-phosphoadenosine 5'-phosphosulfate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP - Drosophila melanogaster [Reaction:R-DME-176646] p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP - Drosophila melanogaster [Reaction:R-DME-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Drosophila melanogaster [Reaction:R-DME-8953499] IMPAD1 hydrolyses PAP to AMP - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Cytosolic sulfonation of small molecules
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-156584
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-156580] Phase II - Conjugation of compounds
(inferredTo)	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules

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