Reactome | phospho-p-S172-TBK1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-3249391] STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] - Drosophila melanogaster [Complex:R-DME-3249391] STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] - Drosophila melanogaster [Complex:R-DME-9824891] p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10873244
displayName	phospho-p-S172-TBK1 [cytosol]
endCoordinate	729
hasModifiedResidue	[ModifiedResidue:10873242] O-phospho-L-serine at 172 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-168379] p-S172-TBK1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-p-S172-TBK1 Q9V3Y8
referenceEntity	[ReferenceGeneProduct:uniprot:Q9V3Y8] UniProt:Q9V3Y8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-168379
startCoordinate	1

(activeUnit)	[CatalystActivity:10873251] protein serine/threonine kinase activity of STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] [CatalystActivity:10906488] protein serine/threonine kinase activity of p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
(hasComponent)	[Complex:R-DME-3249391] STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] [Complex:R-DME-2396005] STING:p-S172-TBK1 [cytoplasmic vesicle membrane] [Complex:R-DME-9824891] p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] [Complex:R-DME-9824890] p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-168379] p-S172-TBK1 [cytosol]