Reactome | ERBB4s80 [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-1253344] ERBB4s80:WWOX [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-1253343] WWOX binds ERBB4s80 - Drosophila melanogaster [BlackBoxEvent:R-DME-1254376] Translocation of cytosolic ERBB4s80 to mitochondrial matrix - Drosophila melanogaster [Reaction:R-DME-1254251] ERBB4s80 binds YAP1 - Drosophila melanogaster [Reaction:R-DME-1254291] ERBB4s80 binds STAT5A - Drosophila melanogaster [BlackBoxEvent:R-DME-1252013] Translocation of ERBB4s80 to the nucleus - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10861417
displayName	ERBB4s80 [cytosol]
hasMember	[Complex:R-DME-1252008] ERBB4jmAcyt1s80 dimer [cytosol] - Drosophila melanogaster [Complex:R-DME-1252007] ERBB4jmAcyt2s80 dimer [cytosol] - Drosophila melanogaster
inDisease	false
inferredFrom	[DefinedSet:R-HSA-1251980] ERBB4s80 [cytosol] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-DME-1253281] ERBB4/ERBB4m80/ERBB4s80 [plasma membrane] - Drosophila melanogaster
name	ERBB4s80 E4ICD
producedByEvent	[Reaction:R-DME-1251997] Cleavage of ERBB4m80 by gamma-scretase complex - Drosophila melanogaster
schemaClass	DefinedSet
species	[Species:56210] Drosophila melanogaster
stId	R-DME-1251980

(hasMember)	[DefinedSet:R-DME-1253281] ERBB4/ERBB4m80/ERBB4s80 [plasma membrane]
(input)	[Reaction:R-DME-1253343] WWOX binds ERBB4s80 [BlackBoxEvent:R-DME-1254376] Translocation of cytosolic ERBB4s80 to mitochondrial matrix [Reaction:R-DME-1254251] ERBB4s80 binds YAP1 [Reaction:R-DME-1254291] ERBB4s80 binds STAT5A [BlackBoxEvent:R-DME-1252013] Translocation of ERBB4s80 to the nucleus
(hasComponent)	[Complex:R-DME-1253344] ERBB4s80:WWOX [cytosol] [Complex:R-DME-1253341] ERBB4s80:YAP1 [cytosol] [Complex:R-DME-1254284] ERBB4s80:p-Y694-STAT5A [cytosol]
(output)	[Reaction:R-DME-1251997] Cleavage of ERBB4m80 by gamma-scretase complex
(inferredTo)	[DefinedSet:R-HSA-1251980] ERBB4s80 [cytosol]