Reactome | Neurotransmitter receptors and postsynaptic signal transmission

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Neurotransmitter receptors and postsynaptic signal transmission Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911030
displayName	Neurotransmitter receptors and postsynaptic signal transmission
eventOf	[Pathway:R-DME-112315] Transmission across Chemical Synapses - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-181431] Acetylcholine binding and downstream events - Drosophila melanogaster [Pathway:R-DME-399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity - Drosophila melanogaster [Pathway:R-DME-442755] Activation of NMDA receptors and postsynaptic events - Drosophila melanogaster [Pathway:R-DME-451326] Activation of kainate receptors upon glutamate binding - Drosophila melanogaster [Pathway:R-DME-977443] GABA receptor activation - Drosophila melanogaster [Reaction:R-DME-975389] GLRA:GLRB:Gly transports extracellular Cl- to cytosol - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-112314] Neurotransmitter receptors and postsynaptic signal transmission - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	6
name	Neurotransmitter receptors and postsynaptic signal transmission
precedingEvent	[Pathway:R-DME-112310] Neurotransmitter release cycle - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-112314
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-112315] Transmission across Chemical Synapses
(hasEncapsulatedEvent)	[Pathway:R-DME-5673001] RAF/MAP kinase cascade
(inferredTo)	[Pathway:R-HSA-112314] Neurotransmitter receptors and postsynaptic signal transmission

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