Reactome | Displacement of DNA glycosylase by APEX1

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Displacement of DNA glycosylase by APEX1 Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10910988
displayName	Displacement of DNA glycosylase by APEX1
eventOf	[Pathway:R-DME-73933] Resolution of Abasic Sites (AP sites) - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-110350] Displacement of TDG glycosylase by APEX1 at the AP site - Drosophila melanogaster [Reaction:R-DME-110351] Displacement of SMUG1 glycosylase by APEX1 at the AP site - Drosophila melanogaster [Reaction:R-DME-110352] Displacement of NTHL1 glycosylase by APEX1 at the AP site - Drosophila melanogaster [Reaction:R-DME-110354] Displacement of OGG1 glycosylase by APEX1 at the AP site - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-110357] Displacement of DNA glycosylase by APEX1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Displacement of DNA glycosylase by APEX1
precedingEvent	[Pathway:R-DME-73927] Depurination - Drosophila melanogaster [Pathway:R-DME-73928] Depyrimidination - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-110357
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-73933] Resolution of Abasic Sites (AP sites)
(inferredTo)	[Pathway:R-HSA-110357] Displacement of DNA glycosylase by APEX1