Reactome | Class I MHC mediated antigen processing & presentation

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Class I MHC mediated antigen processing & presentation Show undefined attributes

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049744
displayName	Class I MHC mediated antigen processing & presentation
eventOf	[Pathway:R-DDI-1280218] Adaptive Immune System - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258522] antigen processing and presentation of peptide antigen via MHC class I
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DDI-983168] Antigen processing: Ubiquitination & Proteasome degradation - Dictyostelium discoideum [Pathway:R-DDI-983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC - Dictyostelium discoideum [Pathway:R-DDI-1236975] Antigen processing-Cross presentation - Dictyostelium discoideum [Pathway:R-DDI-9912633] Antigen processing: Ub, ATP-independent proteasomal degradation - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-983169] Class I MHC mediated antigen processing & presentation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Class I MHC mediated antigen processing & presentation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-983169
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-1280218] Adaptive Immune System
(hasEncapsulatedEvent)	[Pathway:R-DDI-5668599] RHO GTPases Activate NADPH Oxidases
(inferredTo)	[Pathway:R-HSA-983169] Class I MHC mediated antigen processing & presentation

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