Reactome | p-IRAK2:oligo-TRAF6 [endosome membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11014322] ubiquitin-protein transferase activity of p-IRAK2:oligo-TRAF6 [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[BlackBoxEvent:R-DDI-975147] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11014321
displayName	p-IRAK2:oligo-TRAF6 [endosome membrane]
hasComponent	2 × [DefinedSet:R-DDI-450272-25] Homologues of TRAF6 [endosome membrane] [Complex:R-DDI-975108] TRAF6:p-IRAK2 [endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-975137] p-IRAK2:oligo-TRAF6 [endosome membrane] - Homo sapiens
maxDepth	4
name	p-IRAK2:oligo-TRAF6
producedByEvent	[Reaction:R-DDI-975185] IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments - Dictyostelium discoideum
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-975137
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-DDI-975147] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane
(physicalEntity)	[CatalystActivity:11014322] ubiquitin-protein transferase activity of p-IRAK2:oligo-TRAF6 [endosome membrane]
(output)	[Reaction:R-DDI-975185] IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments
(inferredTo)	[Complex:R-HSA-975137] p-IRAK2:oligo-TRAF6 [endosome membrane]