Reactome | Aggresome dissociates from dynein and microtubule

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Aggresome dissociates from dynein and microtubule Show undefined attributes

category	dissociation
compartment	[Compartment:18667] microtubule organizing center
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11044353
displayName	Aggresome dissociates from dynein and microtubule
eventOf	[Pathway:R-DDI-9646399] Aggrephagy - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-9646348] PolyUb-Misfolded Proteins:HDAC6 bind dynein motor - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-9646685] Aggresome dissociates from dynein and microtubule - Homo sapiens
input	[Complex:R-DDI-9646684] Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center]
isInDisease	false
isInferred	true
maxDepth	1
name	Aggresome dissociates from dynein and microtubule
output	[Complex:R-DDI-2029145] Dynein complex [cytosol] [Complex:R-DDI-190599] Microtubule [cytosol] [Complex:R-DDI-9646686] Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-9646685
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-9646399] Aggrephagy
(precedingEvent)	[Reaction:R-DDI-9646348] PolyUb-Misfolded Proteins:HDAC6 bind dynein motor
(inferredTo)	[Reaction:R-HSA-9646685] Aggresome dissociates from dynein and microtubule

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