Reactome | Microtubule [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DDI-983245] Kinesins:microtubule [cytosol] - Dictyostelium discoideum [Complex:R-DDI-5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] - Dictyostelium discoideum
consumedByEvent	[Reaction:R-DDI-8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin - Dictyostelium discoideum [Reaction:R-DDI-9668419] SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites - Dictyostelium discoideum [Reaction:R-DDI-5672329] IQGAP1 binds CLIP1 and microtubules - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11008921
displayName	Microtubule [cytosol]
hasComponent	13 × [Polymer:R-DDI-8982424] Microtubule protofilament [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9833607] microtubule (no TUBA4B) [cytosol] - Homo sapiens [Complex:R-HSA-190599] Microtubule [cytosol] - Homo sapiens
maxDepth	7
name	Microtubule
producedByEvent	[Reaction:R-DDI-9646685] Aggresome dissociates from dynein and microtubule - Dictyostelium discoideum [Reaction:R-DDI-5618331] HDAC6 deacetylates microtubules - Dictyostelium discoideum [Reaction:R-DDI-9836404] p-PKR dimer phosphorylates MAPT - Dictyostelium discoideum
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-190599
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-DDI-5618331] HDAC6 deacetylates microtubules [Reaction:R-DDI-9836404] p-PKR dimer phosphorylates MAPT [Reaction:R-DDI-9646685] Aggresome dissociates from dynein and microtubule
(inferredTo)	[Complex:R-HSA-9833607] microtubule (no TUBA4B) [cytosol] [Complex:R-HSA-190599] Microtubule [cytosol]
(input)	[Reaction:R-DDI-8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin [Reaction:R-DDI-5672329] IQGAP1 binds CLIP1 and microtubules [Reaction:R-DDI-9668419] SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites
(hasComponent)	[Complex:R-DDI-983245] Kinesins:microtubule [cytosol] [Complex:R-DDI-5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] [Complex:R-DDI-2029135] Dynein:Dynactin:microtubule [cytosol] [Complex:R-DDI-8852300] MAPRE1:microtubule plus end [cytosol] [Complex:R-DDI-9619556] MAPT-8:Microtubule [cytosol] [Complex:R-DDI-9646389] PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center]

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