Reactome | Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub

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Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11044277
displayName	Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub
eventOf	[Pathway:R-DDI-9646399] Aggrephagy - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-9641111] Parkin transfers Ub to misfolded proteins - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-9641096] Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub - Homo sapiens
input	[DefinedSet:R-DDI-9640113-3] Homologues of Misfolded CETN1 [cytosol] [Complex:R-DDI-9641092] Ub:UBE2N:UBE2V1:PRKN [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub
output	[Complex:R-DDI-9641099] Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-9641096
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-9646399] Aggrephagy
(precedingEvent)	[Reaction:R-DDI-9641111] Parkin transfers Ub to misfolded proteins
(inferredTo)	[Reaction:R-HSA-9641096] Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub

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